A fully reproducible and state-of-the-art ancient DNA analysis pipeline
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Updated
Feb 20, 2026 - Nextflow
A fully reproducible and state-of-the-art ancient DNA analysis pipeline
A free and easy-to-use pipeline to analyse data from ancient NCR-mtDNA sequences obtained by amplicon-based NGS methods
This project contains a pipeline to analyze raw ancient data, obtained from the sequencing facility. The pipeline includes various Snakemake workflows to process, analyze, and generate reports on the sequence quality, which helps decide if an aDNA extraction and sequencing was successful, and further polishes the data for downstream analyses.
Data and scripts to reproduce the molecular clock dating analyses presented in "Ancient bacterial genomes reveal a formerly unknown diversity of Treponema pallidum strains in early modern Europe (Majander et al.)
Raw code to get polymorphisms from samples analysed by using the PowerSeq® CRM Nested System kit (Promega Corporation)
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