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README.md		README.md
cmd.sh		cmd.sh
cprGeneMutFreq_v5.3.py		cprGeneMutFreq_v5.3.py
cprN1AndTumor_v4.2.3.py		cprN1AndTumor_v4.2.3.py
extract_omega_set_10.py		extract_omega_set_10.py
generate13cds_v4.1.py		generate13cds_v4.1.py

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HCC_mtDNA_evolution

Neutral Evolution of mtDNA in Human Hepatocellular Carcinoma (HCC) based on the samples from different locations of one single tumor tissue.

This work has already been published in Genome Biology and Evolution:

Qi Liu, Deng Lin, Mingkun Li, Zhenglong Gu, Yiqiang Zhao, Evidence of Neutral Evolution of Mitochondrial DNA in Human Hepatocellular Carcinoma, Genome Biology and Evolution, Volume 11, Issue 10, October 2019, Pages 2909–2916, https://doi.org/10.1093/gbe/evz214

The tool in this paper named MitoMutCall for detecting mtDNA heteroplasmies and homoplasmies can be downloaded from: https://github.com/apiaolin/MitoMutCall

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Neutral Evolution of mtDNA in Human Hepatocellular Carcinoma (HCC)

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