Hi there! My name is Lorenzo Sisti and I'm a Biochemist. I’m trained as a computational and structural biologist - although my academic background has a strong biomedical and biomolecular focus. My main research interests lie at the intersection of Biochemistry, Biophysics, and Bioinformatics, with a particular focus on:
- Proteins and antibodies structure, folding and interactions.
- Computational modeling and molecular dynamics (MD) simulations of biomolecules.
After a BS wet-lab thesis internship in Francesca Cutruzzolà's group, where I explored the interactions between metabolic enzymes of the folate cycle and nucleic acids, I joined Jan Dohnálek's Laboratory of Structure and Function of Biomolecules for an internship in crystallography and structural biology. I then transitioned to dry-lab for my MS thesis in Computational Biophysics at the IIT's Center for Life Nano- & Neuro-Science. In parallel, I started collaborating with the Structural Bioinformatics Group at Sapienza University of Rome on molecular dynamics simulations of the DOPA decarboxylase enzyme. Since february 2025 I collaborate with the haematology department of Tor Vergata Hospital as data entry and clinical data manager, and since february 2026 I work as assistant researcher in Lucia Gabriele's Tumor Immunology lab at Istituto Superiore di Sanità, working on both wet-lab and dry-lab projects.