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Add TYQ1 nematode biocontrol SynCom (closes #25)#27

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realmarcin merged 1 commit intomainfrom
add-tyq1-nematode-biocontrol-syncom
Mar 6, 2026
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Add TYQ1 nematode biocontrol SynCom (closes #25)#27
realmarcin merged 1 commit intomainfrom
add-tyq1-nematode-biocontrol-syncom

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@cmungall cmungall commented Mar 5, 2026

Summary

  • Add new community YAML: kb/communities/TYQ1_Nematode_Biocontrol_SynCom.yaml
  • 8-member SynCom centered on keystone species Rhizobium pusense TYQ1, which is enriched during root-knot nematode (Meloidogyne incognita) infection of cucumber
  • TYQ1 recruits 7 biomarker species (Sphingomonas panni, Sphingomonas sp., Acidovorax soli, Acidovorax facilis, Novosphingobium subterraneum, Xenophilus aerolatus, Microbacterium arborescens) that enhance biofilm formation and metabolic cross-feeding for synergistic nematode suppression
  • Based on PMID:41660888 (Liu et al., ISME J. 2025, doi:10.1093/ismejo/wrag022)
  • Validated across 12 soil types; 3 associated BioProject datasets (PRJNA1313845, PRJNA1313795, PRJNA1314495)
  • Passes just validate against the LinkML schema

Closes #25

Test plan

  • just validate kb/communities/TYQ1_Nematode_Biocontrol_SynCom.yaml passes with no issues

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8-member synthetic community centered on keystone Rhizobium pusense TYQ1
for synergistic root-knot nematode suppression in cucumber rhizosphere.
Based on PMID:41660888 (Liu et al., ISME J. 2025).

Closes #25

Co-Authored-By: Claude Opus 4.6 <noreply@anthropic.com>
Copilot AI review requested due to automatic review settings March 5, 2026 15:11
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Pull request overview

Adds a new curated microbial community entry to the knowledge base for the TYQ1-centered nematode biocontrol SynCom described in PMID:41660888, expanding the set of engineered rhizosphere communities represented in kb/communities/.

Changes:

  • Introduces a new community YAML for the TYQ1 Nematode Biocontrol SynCom (engineered rhizosphere SynCom).
  • Captures member taxonomy (8 taxa), interaction summaries, and linked BioProject datasets with evidence snippets.

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Comment on lines +87 to +92
preferred_term: Sphingomonas xanthus SX
term:
id: NCBITaxon:13687
label: Sphingomonas
notes: 'Biomarker species recruited by TYQ1 enrichment (OTU1716). Genus-level NCBITaxon used
as species-level ID not available.
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The Sphingomonas xanthus SX entry uses a genus-level NCBITaxon ID (NCBITaxon:13687, label Sphingomonas) while the preferred_term claims a species-level identification (Sphingomonas xanthus). This is internally inconsistent and can mislead downstream consumers (e.g., taxonomy summaries). Either update the taxon name to genus-level (e.g., Sphingomonas sp./Sphingomonas sp. SX) to match the ID+label, or switch to a species-level NCBITaxon ID if available.

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@realmarcin realmarcin merged commit cfffae2 into main Mar 6, 2026
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@realmarcin realmarcin deleted the add-tyq1-nematode-biocontrol-syncom branch March 6, 2026 09:11
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Add Stress-Induced Rhizobium SynCom for Root-Knot Nematode Suppression

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