Large datasets

[milka1g]

Hello, thank you for this tool.

I am using it on datasets that have a much larger number of observations than the readme tutorial you offered. It finished execution on sample with around 6000 cells and 20 000 genes in about 25min.

When I tried running it on a sample with around 40 000 observations after a few hours I found 'Killed' in tmux. I assume it run out of memory. Do you have any guess if that is too large sample size for this tool or there could be other issues?

Thanks

[Yukaixu666]

I also find this bug, with the increase of sample size, the calculation time become uncontrolled, so, how do you deal with?